The text is highly instructive, but there's no technical jargon and plenty of plot. Scientific mysteries repeatedly force researchers to reexamine their preconceptions. Experiments are often tedious, and the results sometimes puzzling. A finding from an unexpected source may lead to a breakthrough, such as deciphering the genetic code, the surprise of introns, the structure of the ribosome, and catalytic RNA.

Subsequent research opens a world of new possibilities for medicine, like cures for cancer and precise genetic engineering with CRISPR. Cech makes it captivating, with episodes about numerous contributing scientists from near and far. Their dedication is admirable. It's about science at its best.
The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets by Thomas R. Cech, W. W. Norton & Company, 04 Jun 2024.

Actually, Corning combines hyperbole with an informative brief history of the Modern Synthesis to make the case for an "inclusive new synthesis." I propose a different kind of synthesis, one that attempts to characterize the evolutionary process and its key features - the HOW question. ...We need to know where living systems came from, how they got here, how they work, and perhaps where they are going. That sounds promising.

The new synthesis must not ignore a glaring lack: The ongoing evolutionary innovation that life on Earth exhibits has not been demonstrated in controlled experiments. Without proof, the assertion that life's programming (genetic, epigenetic, synergistic, etc.) can somehow invent itself remains an extraordinary claim. A theory in which life arrives, and the programming is acquired, deserves consideration. Otherwise, the new synthesis is not really "inclusive," and Corning's well-posed questions may remain unanswered.

"Evolution" has conflicting meanings. As history, it gets reliable support in the geological record. But as a mechanism behind major (macroevolutionary) advances, the current science is unclear, undemonstrated and unlikely. The surveyors are disappointed by the students' lack of acceptance, "since evolution is going to continue to be central to biological literacy and – scientific literacy – in the 21st century." Which definition do the surveyors have in mind? Recognizing the difference could begin to relieve the gridlock that continues to bind the subject in the 21st century.

When we wonder about life on other worlds, octopuses should come to mind. Most of the liquid water in the solar system is in ice-covered oceans, which sounds favorable for octopuses. A female can produce up to 100,000 eggs the size of rice grains. Protected in icy comets, these eggs could likely endure interplanetary transport. Colleague Ted Steele has reasons to think so.